Science
Mechanism of Action
This ingredient stimulates the production of vital structural proteins like collagen and elastin, alongside hyaluronic acid, within dermal fibroblasts. It also acts as a potent antioxidant, superior to Vitamin C, and reduces pro-inflammatory mediators to prevent 'inflammaging' and protein degradation.
Research
Clinical Evidence
High confidence2%
Key findings
- 01 Increased collagen in aged skin cells and hyaluronic acid in skin, leading to significant firming and smoothing, with histological evidence of increased pro-collagen and GAGs.
- 02 Topical application for 8 weeks visibly improved eye area wrinkles and significantly faded brown/hyperpigmented spots.
- 03 Ex vivo studies demonstrated effective penetration into and through human skin, with approximately 30% absorption from a cream formulation.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Stable across a broad pH range (3–12), commonly found in skin-active formulations from pH 3.5 to 8.2. It integrates well with low-pH AHAs.
Synergies
- Alpha Hydroxy Acids (AHAs)
Conflicts
- High concentrations of electrolytes (potential impact on polymer-based serums)
Safety
Safety Profile
Reviewed by the CIR Expert Panel, it was deemed non-irritating, non-sensitizing, and non-phototoxic. In vitro genotoxicity studies were negative.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Acetyl Tyrosinamide is a valuable ingredient, effectively targeting multiple signs of aging through dermal restructuring, antioxidant protection, and anti-inflammatory action.
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