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Moumoujus

ACETYL TRIHEXYL CITRATE.

Valuable CAS 24817-92-3 / ANTIOXIDANT, CHELATING, PLASTICISER, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Acetyl Trihexyl Citrate is a skin conditioning emollient that enhances skin flexibility and reduces transepidermal water loss. It forms a non-greasy barrier, effectively softening the stratum corneum.

Summary

plasticizer emollient skin conditioning

Science

Mechanism of Action

It functions as an occlusive emollient, integrating into the skin's surface to create a thin, protective barrier. This barrier helps to decrease transepidermal water loss (TEWL), thereby hydrating and softening the skin.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Clinical tests on structurally similar citrate esters (Acetyl Triethyl/Tributyl Citrate) at 100% concentration showed them to be non-irritating and non-sensitizing in humans.
  2. 02 General testing for this class of citrate esters noted an insignificant to low comedogenicity rating, though specific human data for the trihexyl form is limited.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH 4 – 7
0 7 14

Stability

Stable under normal cosmetic conditions. As an ester, it is susceptible to hydrolysis at extreme pH levels (highly acidic or highly alkaline), though it demonstrates greater stability than smaller chain citrates.

Conflicts

  • Strong oxidizing agents
  • Strong bases (may cause saponification/hydrolysis)

Safety

Safety Profile

CIR Status
Safe as used
Max tested
7%
Sensitization risk Low

The CIR Expert Panel concluded Acetyl Trihexyl Citrate is safe as used, reviewing it as part of the Acetyl Trialkyl Citrates group. Historically, specific use data for this form was sparse.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Acetyl Trihexyl Citrate is a safe, effective emollient, offering skin conditioning benefits with low irritancy and comedogenicity for various skin types.

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