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ACETYL TETRAPEPTIDE-69 AMIDE ACETATE.

Valuable / SKIN CONDITIONING

Acetyl Tetrapeptide-69 Amide Acetate is an advanced synthetic signaling peptide designed for anti-aging and skin barrier repair. It helps rejuvenate mature skin by stimulating natural repair processes.

skin conditioning anti-aging improves elasticity strengthens skin barrier

Science

This matrikine-like peptide mimics natural skin fragments, activating endogenous repair mechanisms. It strengthens skin structure and improves elasticity, visibly reducing the appearance of wrinkles.


Research

Medium confidence
Effective range 0.001–0.01%
Optimal

N/A

Key findings

  1. 01 Preliminary in vitro and in vivo studies suggest it stimulates collagen synthesis and enhances epidermal barrier integrity through endogenous repair mechanisms.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 4.5 – 6.5
0 7 14

Stability

Peptides are sensitive to extreme pH levels and high temperatures. Incorporate below 40°C during the cooling phase to prevent hydrolysis.

Conflicts

  • strong oxidizers
  • proteolytic enzymes
  • extreme pH environments (<4.0 or >7.0)

Safety

CIR Status
Not reviewed
Sensitization risk Low

Generally considered safe for topical use at typical peptide concentrations. No specific EU safety restrictions are currently listed in Annex III.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

This peptide is valuable for formulations targeting mature skin regeneration, barrier repair, and visible wrinkle reduction due to its signaling properties and low irritation.


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References