Science
Mechanism of Action
This biomimetic peptide acts as a signaling molecule, promoting cellular proliferation and tissue regeneration. In skin, it stimulates fibroblasts to significantly increase collagen production, while in scalp care, it enhances hair bulb health and follicle activity.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In vitro studies demonstrate significant induction of collagen and pro-collagen synthesis in human dermal fibroblasts, alongside real-time wound healing at 0.0075 µg/ml.
- 02 Clinical protocols report stimulation of hair follicles and epigenetic resumption of the hair bulb, particularly when used with microneedling.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
As a small tetrapeptide, it is relatively stable but sensitive to extreme pH and high heat. Optimal potency is maintained by storing cool (5-25°C), often in lyophilized form.
Conflicts
- Strong oxidizing agents
- Proteolytic enzymes
- Extremely high or low pH environments
Safety
Safety Profile
Listed in the EU CosIng database as a skin and hair conditioning agent, with no documented safety concerns in current literature.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This biomimetic tetrapeptide offers significant regenerative potential for both skin collagen synthesis and hair follicle health, making it a valuable active in advanced formulations.
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References
Sources