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ACETYL HEXAPEPTIDE-20.

Insufficient Data CAS - / SKIN CONDITIONING

This advanced peptide targets key enzymes responsible for collagen and elastin breakdown, while simultaneously enhancing skin hydration. The result is a visibly firmer, more supple, and youthful complexion, resisting signs of chronological and photoaging.

Anti-aging Skin conditioning Moisturizing Firming Elasticity Enhancer Collagen Protection

Science

Acetyl Hexapeptide-20 operates by directly inhibiting skin metalloproteases (MMPs), which are destructive enzymes that degrade vital collagen and elastin fibers. This inhibition leads to an increase in these structural proteins within the skin. Furthermore, it significantly reduces trans-epidermal water loss (TEWL), thereby boosting skin volume, elasticity, and density, and actively contributing to the prevention of both chronological and UV-induced aging.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Unknown
Optimal pH N/A
0 7 14

Safety

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) has not specifically evaluated Acetyl Hexapeptide-20. However, a similar peptide, Acetyl Hexapeptide-8 (also known as Acetyl Hexapeptide-8 Amide), was deemed safe for cosmetic use at concentrations up to 0.005%. Acetyl Hexapeptide-20 is described as 'Irritant Free'.


Your Skin

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Insufficient Data

Despite promising mechanistic data suggesting benefits for skin firmness and hydration, comprehensive clinical efficacy studies and a dedicated CIR review for Acetyl Hexapeptide-20 are currently lacking.


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References