Science
Mechanism of Action
Acetyl Hexapeptide-20 operates by directly inhibiting skin metalloproteases (MMPs), which are destructive enzymes that degrade vital collagen and elastin fibers. This inhibition leads to an increase in these structural proteins within the skin. Furthermore, it significantly reduces trans-epidermal water loss (TEWL), thereby boosting skin volume, elasticity, and density, and actively contributing to the prevention of both chronological and UV-induced aging.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has not specifically evaluated Acetyl Hexapeptide-20. However, a similar peptide, Acetyl Hexapeptide-8 (also known as Acetyl Hexapeptide-8 Amide), was deemed safe for cosmetic use at concentrations up to 0.005%. Acetyl Hexapeptide-20 is described as 'Irritant Free'.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Despite promising mechanistic data suggesting benefits for skin firmness and hydration, comprehensive clinical efficacy studies and a dedicated CIR review for Acetyl Hexapeptide-20 are currently lacking.
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References
Sources