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ACETAMINOSALOL.

Insufficient Data CAS 118-57-0 / ANTIMICROBIAL, UV ABSORBER

Acetaminosalol is an organic compound that serves primarily as an antimicrobial preservative within cosmetic formulations. It acts as a prodrug, undergoing gradual decomposition, particularly in alkaline environments, to release its active components: salicylic acid and paracetamol.

Antimicrobial Preservative UV Absorber

Science

In the context of skincare, Acetaminosalol functions by progressively releasing salicylic acid and paracetamol, specifically when exposed to alkaline conditions. This controlled decomposition pathway enables its primary role as an effective antimicrobial preservative, inhibiting the growth of microorganisms and thus extending the product's shelf life.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Acetaminosalol is practically insoluble in cold water and petroleum ether. It exhibits solubility in alcohol, ether, and benzene, but critically, it decomposes in alkaline solutions.

Conflicts

  • alkaline solutions

Safety

CIR Status
Not reviewed
Sensitization risk Moderate

Acetaminosalol itself has not been subject to a direct review by the Cosmetic Ingredient Review (CIR Expert Panel). However, its constituent, Salicylic Acid, has been evaluated and deemed safe for cosmetic applications when formulated to be non-irritating and non-sensitizing. Global Harmonized System (GHS) classifications indicate that Acetaminosalol may pose a risk of allergic skin reaction (Skin Sens. 1) and serious eye irritation (Eye Irrit. 2). No direct SCCS opinion or FDA cosmetic use status for Acetaminosalol has been identified.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Insufficient Data

Further targeted research is necessary to fully assess Acetaminosalol's safety and efficacy profile for optimal use in advanced skincare formulations.


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