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ACETALDEHYDE DIETHYL ACETAL.

Questionable CAS 105-57-7 / PERFUMING

A dual-function ingredient serving as both a fragrance component and solvent in cosmetic formulations. This synthetic compound exhibits notable pH sensitivity, remaining stable in alkaline conditions but breaking down into acetaldehyde and ethanol in acidic environments, potentially causing skin irritation.

perfuming solvent

Science

Functions primarily as a perfuming agent and solvent system. Upon contact with acidic skin environments, undergoes hydrolysis to release acetaldehyde and ethanol, which can disrupt the skin barrier and trigger inflammatory responses in sensitive individuals.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Limited use in skincare formulations due to irritation potential and regulatory restrictions


The Formula

Solubility
Both
Optimal pH 7.4 – 10
0 7 14

Stability

Exhibits high pH sensitivity with optimal stability in alkaline conditions (pH 7.4-10.0). Rapid hydrolysis occurs below pH 7.0, compromising both efficacy and safety profiles.

Conflicts

  • Acidic ingredients
  • Oxidizing agents
  • Strong acids
  • Heat sources

Safety

CIR Status
Not reviewed
Sensitization risk Moderate

FDA recognizes as impurity in alcohol with <10 ppm limit. FEMA-GRAS status for food flavoring but lacks established safety thresholds for topical leave-on applications.


Your Skin

Yes Normal
No Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Low

Our Assessment

Questionable

Limited skincare value due to moderate irritation potential and pH-dependent stability issues that compromise formulation reliability.


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