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7-DEHYDROCHOLESTERYL PALMITATE.

Insufficient Data / SKIN PROTECTING, UV FILTER

A stabilized ester derivative of 7-dehydrocholesterol that functions as a provitamin D3 precursor in topical formulations. When exposed to UVB radiation, it converts to vitamin D3 in the skin, supporting barrier function and cellular differentiation while providing supplemental UV protection.

skin protecting uv filter vitamin d precursor

Science

Functions as a stable precursor to vitamin D3 that undergoes photochemical conversion when exposed to UVB radiation (290-315 nm). The resulting vitamin D3 synthesis promotes skin barrier integrity, enhances cellular differentiation processes, and provides protective benefits against UV-induced damage.


Research

Low confidence
Effective range 0.1–1%
Optimal

N/A


Transparency

Not commonly dusted

Limited clinical data suggests genuine use in sunscreen and serum formulations at meaningful concentrations rather than trace amounts


The Formula

Solubility
Oil
Optimal pH 5 – 8
0 7 14

Stability

More stable than base 7-dehydrocholesterol but remains photosensitive and oxidation-prone. Requires opaque, airtight packaging to prevent sterol ring degradation.

Synergies

  • UV filters
  • barrier repair ingredients

Conflicts

  • Strong oxidizing agents
  • Highly acidic formulations

Safety

CIR Status
Not reviewed
Sensitization risk Low

Approved for cosmetic use in EU and China databases. Generally well-tolerated at current usage levels in commercial products.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Insufficient Data

Promising vitamin D precursor concept with broad skin compatibility but lacks robust standalone clinical validation.


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References