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Moumoujus

7-AMINO DIHYDROBENZOTHIAZINE.

Insufficient Data CAS 1888767-40-5 / HAIR DYEING

A specialized hair dye intermediate that mimics natural melanin precursors found in the pheomelanin synthesis pathway. This aromatic amine compound works as a coupler in oxidative hair coloring systems, reacting with hydrogen peroxide and primary intermediates to create stable pigment molecules within the hair shaft. While primarily developed for hair applications, its structural relationship to natural pigmentation pathways makes it an interesting compound for cosmetic formulation research.

Summary

hair dyeing agent oxidative coupler

Science

Mechanism of Action

Functions as an oxidative coupler that undergoes chemical transformation in the presence of hydrogen peroxide and alkaline conditions. The compound reacts with primary intermediates to form larger chromophore molecules that become trapped within hair or potentially other protein structures, creating lasting color changes through covalent bond formation.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Research demonstrates dihydrobenzothiazine derivatives serve as key intermediates in pheomelanin biosynthesis, with specific conversion to benzothiazole structures during natural pigment formation processes

Transparency

Dusting Analysis

Not commonly dusted

This ingredient is specifically regulated for hair dyeing applications and not commonly found in general skincare formulations, making dusting practices irrelevant for typical cosmetic products.

The Formula

Formulation

Solubility
Water
Optimal pH 9 – 11
0 7 14

Stability

Requires oxygen-free environment and alkaline conditions for stability. Typically formulated as hydrochloride or sulfate salts to enhance water solubility and prevent premature oxidation.

Synergies

  • Primary hair dye intermediates
  • Alkaline agents

Conflicts

  • Oxidizing agents
  • Strong acids

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Regulated under EU Annex III as an aromatic amine for hair dyeing. Belongs to a strictly controlled ingredient class due to potential sensitization concerns typical of oxidative hair dye components.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Limited to specialized hair applications with insufficient safety data for general skincare use.

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