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4-METHYLPENTAN-2-OL.

Optional CAS 108-11-2 / PERFUMING

4-Methylpentan-2-ol, also known as Methyl Isobutyl Carbinol (MIBC), is a secondary aliphatic alcohol that serves dual functions as a fragrance component and solvent in cosmetic formulations. This ingredient features a distinctive mild, oily-green scent profile while enhancing product texture through its viscosity-reducing properties. Its molecular structure enables effective dissolution and transport of fragrance oils throughout formulations.

perfuming solvent

Science

Functions primarily through solvent action, reducing formulation viscosity and serving as an efficient carrier vehicle for fragrance compounds. Upon skin contact, the molecule facilitates even distribution of active ingredients while contributing its characteristic scent profile. The body metabolizes this compound through a two-step process, first converting it to methyl isobutyl ketone (MIBK), then to 4-hydroxy-4-methyl-2-pentanone.


Research

Medium confidence
Effective range ≤0.0015%
Optimal

0.000018%

Key findings

  1. 01 RIFM 2024 safety assessment found no skin sensitization concerns at 95th percentile usage concentration of 0.000018% in hydroalcoholic products

Transparency

Not commonly dusted

Used at extremely low concentrations (0.000018%) primarily for fragrance purposes, making dusting unlikely and unnecessary


The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Demonstrates stability under standard storage conditions but requires careful handling due to flammable nature (flash point 41°C). Long-term air exposure may lead to explosive peroxide formation, necessitating proper storage protocols.

Conflicts

  • Oxidizing agents
  • Strong acids
  • Acid chlorides

Safety

CIR Status
Not reviewed
Max tested
0.0015%
Sensitization risk Low

RIFM assessments confirm safety at current usage levels. Higher concentrations may cause ocular and respiratory irritation. OECD SIDS data indicates no skin sensitization potential.


Your Skin

Yes Normal
No Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Optional

A functional fragrance ingredient that's safe at current usage levels but offers limited unique benefits beyond scent contribution.


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