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4-METHYLBENZYLIDENE CAMPHOR.

Avoid CAS 36861-47-9 / 38102-62-4 / LIGHT STABILIZER, UV ABSORBER, UV FILTER

A chemical UV filter that absorbs UVB radiation and stabilizes other sunscreen ingredients, though recent safety evaluations have raised significant concerns. While historically used at concentrations up to 4%, emerging research reveals systemic absorption and potential endocrine disruption that has led to regulatory restrictions.

UV filter UV absorber Photostabilizer

Science

Absorbs UVB radiation between 290-320 nm with peak effectiveness at 301 nm, converting harmful UV energy into harmless heat while also stabilizing photosensitive ingredients like avobenzone in sunscreen formulations.


Research

Medium confidence
Effective range ≤4%
Optimal

4%

Key findings

  1. 01 SCCS 2022 re-evaluation found higher systemic exposure than previously estimated at 4% concentration
  2. 02 Human pharmacokinetics study (Janjua 2008) demonstrated peak plasma levels within 6 hours of application
  3. 03 Animal studies showed endocrine disruption at 33 mg/kg oral dose with thyroid hormone interference

Transparency

Not commonly dusted

Not applicable for UV filters as they require specific concentrations for efficacy


The Formula

Solubility
Oil
Optimal pH 5 – 7.2
0 7 14

Stability

Crystalline solid at room temperature with moderate photostability (10% degradation in 65 minutes). Maintains stability for 4+ years in original form.

Synergies

  • Avobenzone (photostabilization)

Conflicts

  • Highly aqueous systems without solubilizing agents
  • Ethanol or glycol pre-dissolution required for water-based formulations

Safety

CIR Status
Not reviewed
Max tested
4%
Pregnancy
Caution
Sensitization risk Low

Banned in EU (May 2025 for new products, May 2026 complete ban) due to endocrine disruption and genotoxicity concerns. Not FDA-approved in US. Approved in Australia and Canada up to 4%.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Avoid

Despite effective UVB protection, systemic absorption and endocrine disruption risks make this ingredient unsuitable for precision skincare formulations.


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