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Moumoujus

4-HYDROXYBUTYL ACRYLATE.

Questionable CAS 2478-10-6 / BINDING

A reactive monomer that polymerizes to form flexible, film-forming structures in cosmetic formulations, primarily used in nail products and adhesive applications. While effective for creating durable, scratch-resistant films, it carries inherent sensitization risks due to its reactive acrylate chemistry. Most commonly encountered in UV-curable nail polishes and specialized adhesive products rather than traditional skincare.

Summary

monomer film former adhesive

Science

Mechanism of Action

Functions as a building block for polymer networks through its reactive acrylate group, while the hydroxyl group enables crosslinking and enhances adhesion to skin surfaces, creating flexible films with superior durability

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Occupational dermatology study (2022) identified as contact allergen in UV-cured products
  2. 02 Biomedical adhesives research (2022) demonstrated high adhesion and flexibility in medical applications

Transparency

Dusting Analysis

Not commonly dusted

Primarily used as a specialized monomer in specific applications like nail products rather than being added to inflate ingredient lists

The Formula

Formulation

Solubility
Water
Optimal pH ≥6.5
0 7 14

Stability

Highly reactive with tendency toward spontaneous polymerization; requires MEHQ stabilization and oxygen presence for stability; shows better hydrolytic stability than shorter-chain acrylates

Conflicts

  • Peroxides
  • Strong oxidizing agents
  • Strong acids
  • Strong bases
  • Copper
  • Iron (III) ions

Safety

Safety Profile

CIR Status
Safe with restrictions
Sensitization risk High

Classified as skin irritant (GHS Category 2) and skin sensitizer (Category 1) in pure form; safer when incorporated into properly formulated polymer systems

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

A specialized ingredient with high sensitization potential that's better suited for specific applications like nail products rather than general skincare formulations.

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References

Sources