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4,4'-ISOPROPYLIDENEDIPHENYL/EPICHLOROHYDRIN COPOLYMER DIACRYLATE.

Questionable / NAIL CONDITIONING

A synthetic polymer that functions as a film-forming agent and resin in cosmetic formulations, creating durable, water-resistant barriers on skin and nails. Also known as Bisphenol A Diglycidyl Ether Diacrylate, it undergoes UV-initiated polymerization to form strong adhesive films. While effective for long-wearing formulations, it requires careful handling due to its potent sensitization potential.

Film Forming Nail Conditioning Adhesive

Science

Forms cross-linked polymer networks through UV or radical-initiated polymerization, creating mechanical barriers that provide adhesion, water resistance, and structural integrity to cosmetic films and coatings


Research

Medium confidence
Effective range 0.1–5%
Optimal

N/A

Key findings

  1. 01 Threshold level for sensitization patch testing in occupational exposure studies
  2. 02 Maximum safe concentration proposed for medical preparations to minimize Type IV hypersensitivity risk

Transparency

Not commonly dusted
Red flag below
5%

Primarily used in specialized applications like nail care and waterproof cosmetics rather than general skincare; concentrations above 5% present significant sensitization risks


The Formula

Solubility
Oil
Optimal pH 4 – 11.5
0 7 14

Stability

Stable under inert conditions but photosensitive and thermally reactive, triggering premature polymerization when exposed to UV light or heat

Conflicts

  • Strong oxidizing agents
  • Free radical initiators
  • Strong acids
  • Peroxides

Safety

CIR Status
Safe with restrictions
Max tested
5%
Sensitization risk High

Category 1 skin sensitizer requiring complete polymerization to minimize allergen risk from residual monomers; FDA-approved as indirect food additive for coatings


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Low

Our Assessment

Questionable

Effective film-former for specialized applications but high sensitization risk limits broader skincare utility.


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