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3-PHENYLBUTYRALDEHYDE.

Optional CAS 16251-77-7 / PERFUMING

3-Phenylbutyraldehyde is an aromatic aldehyde primarily employed as a fragrance component in skincare formulations, delivering a distinctive green foliage and hyacinth-like scent profile. While it serves no direct therapeutic skin benefits, this ingredient is commonly incorporated into anti-aging compositions and various cosmetic products for its olfactory properties.

perfuming

Science

Functions exclusively as a perfuming agent with no established skin-active mechanism. In biochemical contexts, it undergoes oxidative modification via cytochrome P450 enzymes, but this process is not relevant to its cosmetic application.


Research

Low confidence
Effective range 0.1–2.7%
Optimal

N/A

Key findings

  1. 01 Patent literature documents use at 0.1-1.0% as fragrance component in anti-aging formulations with L-ascorbic acid derivatives
  2. 02 RIFM safety assessment established 5900 μg/cm2 as No Expected Sensitization Induction Level via human repeat insult patch testing

Transparency

Not commonly dusted

As a fragrance ingredient with established IFRA concentration limits, dusting is not a primary concern for this component.


The Formula

Solubility
Both
Optimal pH 4 – 7
0 7 14

Stability

Aldehydes are susceptible to oxidation forming carboxylic acids; demonstrates stability in micro-emulsions and alcohol-free formulations between 4°C-50°C when supplied in dipropylene glycol

Conflicts

  • Strong oxidizing agents
  • Strong bases
  • Primary amines (forms Schiff bases)

Safety

CIR Status
Not reviewed
Max tested
2.7%
Sensitization risk Moderate

Regulated by IFRA standards with category-specific limits: 0.17% in lip products, 0.22% in deodorants, up to 2.7% in perfumes. Identified as potential skin sensitizer.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Optional

A functional fragrance ingredient with moderate sensitization potential that adds sensory appeal but no therapeutic value to skincare formulations.


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