Science
Mechanism of Action
Functions as an emollient by creating a protective barrier on skin to reduce transepidermal water loss, while simultaneously offering mild anti-inflammatory activity through inhibition of specific inflammatory mediators, contributing to the calming properties associated with chamomile extracts.
Research
Clinical Evidence
High confidence1%
Key findings
- 01 48-hour occlusive patch testing at 4.0% showed no irritation or sensitization in 25 volunteers
- 02 Testing at 5.0% in 290 eczema patients resulted in only one adverse reaction (0.34% sensitization rate)
- 03 At 0.4% in face cream formulation, contributed to 60% reduction in inflammation and 30-35% decrease in skin sensitivity over 7 days
Transparency
Dusting Analysis
Typically used as a natural component of chamomile essential oil rather than as a standalone ingredient, making dusting less relevant for this compound.
The Formula
Formulation
Stability
Susceptible to hydrolysis under extreme pH conditions, breaking down into angelic acid and 3-methylpentanol; remains stable within typical cosmetic pH ranges
Synergies
- Roman chamomile oil constituents
- Other anti-inflammatory botanicals
- Emollient systems
Conflicts
- Strong oxidizing agents
- Strongly alkaline ingredients (pH > 9.0)
- Strongly acidic ingredients (pH < 3.0)
Safety
Safety Profile
CIR Expert Panel concluded Anthemis nobilis-derived ingredients are safe in current usage practices; 10% limit applies to flower water, essential oils typically used below 1% in leave-on products
Your Skin
Skin Compatibility
Our Assessment
Verdict
A well-tolerated, naturally-derived multifunctional ingredient that combines gentle emollient properties with mild anti-inflammatory benefits and pleasant sensory attributes.
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References
Sources