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Moumoujus

3-ETHYLPHENOL.

Optional CAS 620-17-7 / PERFUMING

A phenolic compound that serves dual functions as a fragrance ingredient and antimicrobial agent in cosmetic formulations. While structurally capable of disrupting microbial cell membranes, its primary application in skincare remains as a scent component at carefully controlled concentrations.

Summary

fragrance antimicrobial

Science

Mechanism of Action

Functions through phenolic activity that can interfere with microbial cell membrane integrity and protein structure, while contributing aromatic properties to formulations at low concentrations used in consumer products.

Research

Clinical Evidence

Medium confidence
Effective range 0.01–0.08%
Optimal

0.08%

Key findings

  1. 01 Established safety threshold for systemic exposure with NOAEL of 100 mg/kg/day in repeated dose toxicity studies, supporting safe use at current fragrance levels

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
0.1%
Red flag below
1%

Rarely featured prominently due to its specialized fragrance function and safety considerations at higher concentrations

The Formula

Formulation

Solubility
Both
Optimal pH 4 – 7
0 7 14

Stability

Demonstrates limited water solubility (3.3 g/L) with enhanced solubility in alcoholic and oil phases; requires protection from prolonged air and light exposure to prevent oxidative degradation

Conflicts

  • Strong oxidizing agents
  • Strong bases
  • Acid chlorides
  • Acid anhydrides

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
1%
Sensitization risk Moderate

ECHA classifies pure substance as skin toxic and corrosive (H314); consumer product usage typically restricted below 0.1% for fragrance applications with structural analogue p-Ethylphenol under IFRA monitoring

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Low

Our Assessment

Verdict

Optional

A specialized fragrance ingredient with antimicrobial properties that requires careful concentration control and is unsuitable for sensitive skin applications.

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References

Sources