Science
Mechanism of Action
Functions as a precursor molecule that undergoes oxidative coupling reactions, combining with primary intermediates in the presence of hydrogen peroxide to form large pigment complexes that become trapped within hair fibers
Research
Clinical Evidence
High confidence2%
Key findings
- 01 SCCNFP safety evaluation at 2.0% concentration in permanent hair dye formulations
- 02 SCCP toxicological assessment confirming maximum non-lethal dose of 300 mg/kg in animal studies
Transparency
Dusting Analysis
Restricted to hair coloring applications with specific concentration limits, not commonly found in general skincare formulations
The Formula
Formulation
Stability
Hydrochloride salt form enhances stability and handling characteristics, remains stable during oxidative dyeing when combined with hydrogen peroxide in 1:1 ratios
Synergies
- Hydrogen peroxide
- Primary dye intermediates
Conflicts
- Strong oxidizing agents (outside intended dye reactions)
- Strong alkaline compounds
Safety
Safety Profile
EU regulations permit maximum 3.0% in oxidative hair dye formulations (1.5% on-head dilution). Known skin sensitizer requiring warning labels, potential for severe ocular irritation
Your Skin
Skin Compatibility
Our Assessment
Verdict
Specialized hair dyeing ingredient with significant sensitization risks and no established skincare benefits.
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References
Sources