Science
Mechanism of Action
Disrupts microbial cell membrane integrity while inhibiting inflammatory mediator production via the 5-LOX pathway, specifically reducing leukotriene B4 formation. Additionally scavenges free radicals to mitigate oxidative stress-induced tissue damage.
Research
Clinical Evidence
Medium confidence2.5%
Key findings
- 01 MIC range of 0.78-6.25% demonstrated effectiveness against S. aureus and skin pathogens in lemongrass essential oil studies
- 02 2.5% concentration identified as minimum effective level for antifungal cream formulations
Transparency
Dusting Analysis
Often added in trace amounts for fragrance masking rather than therapeutic benefit, with IFRA restrictions limiting meaningful antimicrobial concentrations in face products to 0.12%
The Formula
Formulation
Stability
Exhibits high volatility and oxidation susceptibility, particularly under light and air exposure. Requires stabilization through pickering emulsions or nanoemulsion technology.
Conflicts
- Silver ions
- Strong oxidizing agents
- Strong acids and bases
Safety
Safety Profile
IFRA Category 5B restriction limits use to 0.12% in facial moisturizers. NESIL established at 7000 μg/cm2. FDA GRAS status for flavoring applications only.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Limited to subtherapeutic concentrations in skincare due to sensitization concerns, making it more suitable as a fragrance component than active ingredient.
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References
Sources