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2-UNDECENENITRILE.

Optional CAS 22629-48-7 / PERFUMING

A specialized fragrance ingredient that functions primarily as a scent modifier and fixative in cosmetic formulations. This nitrile compound excels at masking unwanted base odors while extending the longevity of more volatile fragrance components. Its robust chemical stability makes it particularly valuable in challenging formulation environments.

perfuming fragrance modifier odor masking

Science

Functions through odor masking and fragrance fixation rather than direct skin interaction. The molecule's nitrile structure provides exceptional stability, allowing it to bind and modify volatile fragrance compounds while potentially offering minor antioxidant properties, though skin-specific benefits remain unestablished.


Research

Medium confidence
Effective range ≤0.69%
Optimal

N/A

Key findings

  1. 01 RIFM safety assessment (2022) established NESIL at 0.69% concentration (6900 μg/cm²) for skin sensitization threshold

Transparency

Not commonly dusted

Primarily used as fragrance component at very low concentrations, not typically subject to dusting practices in skincare formulations


The Formula

Solubility
Oil
Optimal pH 4 – 9
0 7 14

Stability

Exceptionally stable across pH ranges, resistant to oxidation and hydrolysis in both alkaline and acidic environments

Conflicts

  • Strong oxidizing agents
  • Strong reducing agents

Safety

CIR Status
Not reviewed
Max tested
0.1%
Sensitization risk Moderate

Regulated under IFRA standards with established sensitization potential. Commercial use typically maintained below 0.1% to remain under dermal sensitization threshold.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Optional

A functional fragrance ingredient with established safety parameters but limited direct skincare benefits beyond sensory enhancement.


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