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Moumoujus

2-UNDECENAL.

Optional CAS 2463-77-6 / 53448-07-0 / PERFUMING

A medium-chain unsaturated aldehyde primarily utilized as a fragrance component in cosmetic formulations. This fatty aldehyde demonstrates antimicrobial properties through membrane disruption mechanisms while serving as a perfuming agent. Clinical testing at concentrations up to 2% has shown acceptable tolerance profiles in human subjects.

Summary

perfuming antimicrobial

Science

Mechanism of Action

Functions primarily as a perfuming agent while exhibiting antimicrobial activity through disruption of microbial cell membranes. At elevated concentrations, may interact with skin proteins or affect intracellular glutathione levels, potentially leading to oxidative stress responses.

Research

Clinical Evidence

Medium confidence
Effective range 0.2–2%
Optimal

1%

Key findings

  1. 01 Human patch testing at 2% showed no sensitization in 53 subjects (RIFM 2022)
  2. 02 Keratinocyte viability maintained at 90-360 µg/mL over 48 hours (MDPI 2024)
  3. 03 No sensitization reactions at 0.2% in 105 volunteers using trans-2-decenal read-across data

Transparency

Dusting Analysis

Not commonly dusted

Primarily used as a fragrance ingredient rather than active component, unlikely to be subject to dusting practices

The Formula

Formulation

Solubility
Oil
Optimal pH 5 – 9
0 7 14

Stability

Demonstrates stability in oil-based systems and emulsions but requires protection from oxidation due to aldehyde structure. Antioxidants like alpha-tocopherol enhance stability. Requires refrigerated storage at 2-8°C in sealed containers.

Synergies

  • Alpha-tocopherol
  • Other antioxidants

Conflicts

  • Strong oxidizing agents
  • Strong bases
  • Strong acids

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
1%
Sensitization risk Moderate

Classified as skin irritant (GHS H315) and potential sensitizer (GHS H317). RIFM NESIL established at 230 μg/cm². Generally limited to 1% in fragrance concentrates.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Optional

A functional fragrance ingredient with antimicrobial properties but limited to non-sensitive skin types due to moderate irritation potential.

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