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Moumoujus

2-METHYLNAPHTHALENE.

Avoid CAS 91-57-6 / PERFUMING

A polycyclic aromatic hydrocarbon primarily found as a fragrance component or industrial intermediate in cosmetic formulations. This crystalline compound demonstrates significant dermal absorption capabilities but raises substantial safety concerns due to its potential for systemic toxicity and sensitization. Its presence in skincare products is typically limited to trace amounts within fragrance mixtures rather than as an active ingredient.

Summary

perfuming

Science

Mechanism of Action

Functions by binding to aryl hydrocarbon receptors (AhR) and inducing cytochrome P450 enzymes (CYP1A1, CYP1A2), leading to metabolite formation that can interact with cellular proteins and DNA, potentially triggering oxidative stress pathways

Research

Clinical Evidence

High confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Demonstrated significant dermal absorption leading to pulmonary toxicity in murine models
  2. 02 High-dose application resulted in severe bronchiolar injury and systemic toxicity with recovery observed after 7 days

Transparency

Dusting Analysis

Commonly dusted
Min. effective
0.01%
Red flag below
0.1%

Often added in minimal concentrations within fragrance blends to mask its presence while maintaining olfactory properties, requiring careful label scrutiny

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Volatile crystalline solid with high lipophilicity (logP ~3.86) that decomposes upon heating, releasing irritating fumes

Conflicts

  • Strong oxidizing agents

Safety

Safety Profile

CIR Status
Not reviewed
Pregnancy
Caution
Sensitization risk High

Listed on California Safe Cosmetics Program as potentially toxic compound with R42/43 classification for harmful and sensitizing properties

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

A concerning ingredient with significant toxicity potential and no established skincare benefits that should be avoided in precision formulations.

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