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2-METHYLBUTYL ISOVALERATE.

Optional CAS 2445-77-4 / PERFUMING

A naturally occurring fatty acid ester that delivers sophisticated apple and berry fragrance notes to skincare formulations. This volatile compound serves primarily as a perfuming agent, offering excellent stability in cream and lotion matrices while maintaining broad skin type compatibility.

perfuming

Science

Functions as a fragrance component through its inherent fruity-herbaceous odor profile, while undergoing enzymatic hydrolysis by skin esterases to yield 2-methylbutanol and isovaleric acid metabolites.


Research

High confidence
Effective range 0.1–4%
Optimal

1.6%

Key findings

  1. 01 Maximum recommended usage in fragrance applications with non-sensitizing profile
  2. 02 Demonstrated irritation index of 0.04 in hops extract applications

Transparency

Not commonly dusted

Primarily used as fragrance component at established safe levels rather than marketed for therapeutic benefits


The Formula

Solubility
Oil
Optimal pH 4 – 8
0 7 14

Stability

Demonstrates excellent stability in alcoholic and emulsion systems, with potential hydrolysis concerns in highly alkaline environments due to ester bond vulnerability

Conflicts

  • Strong oxidizing agents
  • Strong bases
  • Strong acids

Safety

CIR Status
Safe as used
Max tested
4%
Pregnancy
Safe
Sensitization risk Low

Classified as Cramer Class I with low toxicity profile and no expected genotoxic, photoirritating, or photoallergenic potential


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Optional

A well-tolerated fragrance ingredient suitable for all skin types when aesthetic enhancement through apple-berry scent notes is desired.


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References