Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

2-METHYL-5-HYDROXYETHYLAMINOPHENOL.

Questionable CAS 55302-96-0 / HAIR DYEING

A synthetic aromatic amine compound primarily functioning as a coupler in oxidative hair coloring systems. This secondary intermediate reacts with primary dye precursors in the presence of hydrogen peroxide to create permanent color molecules within the hair shaft. While approved for hair dye applications, its potential for sensitization requires careful formulation considerations.

Summary

Hair dyeing Color coupling agent

Science

Mechanism of Action

Acts as a coupling agent that undergoes oxidative reactions with primary intermediates to form large, stable pigment molecules that become trapped within the hair structure, creating permanent coloration.

Research

Clinical Evidence

High confidence
Effective range 1.25–1.5%
Optimal

1.5%

Key findings

  1. 01 SCCS safety assessment at 1.5% concentration with hydrogen peroxide
  2. 02 Patch testing at 17% showing minimal sensitization in 100 subjects
  3. 03 Contact allergy study at 1.25% demonstrating lower sensitization potential than p-toluenediamine

Transparency

Dusting Analysis

Not commonly dusted

Primarily used in hair coloring applications with established concentration limits; not commonly found in skincare formulations

The Formula

Formulation

Solubility
Water
Optimal pH 6 – 8
0 7 14

Stability

Maintains stability under standard storage conditions but exhibits high reactivity with oxidizing agents. Vulnerable to nitrosation reactions due to secondary amine structure.

Synergies

  • Primary hair dye intermediates
  • Hydrogen peroxide for color development

Conflicts

  • Oxidizing agents (outside intended use)
  • Nitrosating compounds

Safety

Safety Profile

CIR Status
Safe as used
Max tested
1.5%
Sensitization risk Moderate

Maximum 1.5% refers to on-head concentration after mixing with developer. Classified as potential skin sensitizer requiring allergy testing warnings.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

Effective hair dye coupler with established safety profile, but limited skincare applications and moderate sensitization risk make it unsuitable for precision skincare formulations.

Related

Similar Ingredients

Finding similar ingredients…