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2-HEPTANOL.

Optional CAS 543-49-7 / PERFUMING

2-Heptanol is a secondary fatty alcohol that functions primarily as a fragrance component and solvent in cosmetic formulations. This compound offers mild antibacterial properties while serving as a penetration enhancer, though its potential to disrupt the skin's lipid barrier requires careful formulation considerations.

perfuming solvent antimicrobial

Science

Functions as a dual-purpose ingredient that disrupts bacterial cell membranes to provide antimicrobial effects while acting as a lipid-disrupting solvent that can enhance the penetration of other active ingredients, though this defatting action may compromise barrier function at higher concentrations.


Research

Low confidence
Effective range 0.1–5%
Optimal

2.5%

Key findings

  1. 01 In vitro antibacterial activity demonstrated at 0.1-5% concentrations
  2. 02 Maximum safe usage level established at 5.0% in fragrance applications

Transparency

Not commonly dusted

Not typically used as a marketing ingredient due to its functional role as solvent and fragrance component rather than active skincare benefit


The Formula

Solubility
Both
Optimal pH 4 – 8
0 7 14

Stability

Demonstrates good stability across standard cosmetic pH ranges with water solubility of 3.3-4.5 g/L and high compatibility with ethanol and oil phases

Synergies

  • AHA compounds (as solvent enhancer)
  • Other fragrance components

Conflicts

  • Strong oxidizing agents

Safety

CIR Status
Not reviewed by CIR
Max tested
5%
Sensitization risk Moderate

ECHA classifies as skin and eye irritant in concentrated form; recognized as FEMA GRAS flavoring agent but requires concentration limits for topical use


Your Skin

Yes Normal
No Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Low

Our Assessment

Optional

A functional ingredient with limited skincare benefits that serves specific solvent and fragrance needs but requires careful concentration management due to irritation potential.


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References