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Moumoujus

2-ETHYLBUTANOL.

Optional CAS 97-95-0 / PERFUMING

A branched-chain alcohol primarily utilized as a solvent and fragrance intermediate in skincare formulations. This oil-soluble compound can temporarily enhance ingredient penetration through the skin barrier while serving as a building block for complex fragrance molecules.

Summary

Solvent Fragrance intermediate Penetration enhancer

Science

Mechanism of Action

Functions as a penetration enhancer by temporarily disrupting the lipid bilayer structure of the stratum corneum, allowing improved delivery of active ingredients. Additionally serves as an effective solvent for oils, waxes, and fragrance compounds within formulations.

Research

Clinical Evidence

Medium confidence
Effective range 0.001–1.7%
Optimal

1.7%

Key findings

  1. 01 RIFM safety assessment demonstrated non-irritating properties and low sensitization potential at concentrations up to 1.7%
  2. 02 Toxicological evaluation showed no skin irritation at concentrations between 2-10% in human subjects

Transparency

Dusting Analysis

Not commonly dusted

Primarily functions as a processing aid and fragrance component rather than an active ingredient, making dusting practices uncommon for this compound.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Maintains stability under standard cosmetic conditions but becomes susceptible to esterification and dehydration reactions in highly acidic environments. Low freezing point contributes to formulation stability in cold conditions.

Synergies

  • Fragrance compounds
  • Oil-based actives requiring solubilization

Conflicts

  • Strong oxidizing agents
  • Strong acids

Safety

Safety Profile

CIR Status
Not individually reviewed but falls under branched chain saturated alcohols category
Max tested
1.7%
Sensitization risk Low

RIFM safety assessment supports current usage practices at concentrations below 1.7% with minimal irritation or sensitization concerns.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Optional

A functionally useful but non-essential ingredient serving primarily as a processing aid and fragrance component with established safety at typical use levels.

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References

Sources