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Moumoujus

2-DODECENOL.

Questionable CAS 22104-81-0 / PERFUMING

A twelve-carbon unsaturated fatty alcohol primarily employed as a fragrance component and secondary emollient in specialized formulations. This long-chain alcohol provides occlusive properties to reduce transepidermal water loss while contributing to the sensory profile of cosmetic products. Due to its unsaturated structure, it requires careful formulation considerations to prevent oxidative degradation.

Summary

fragrance emollient

Science

Mechanism of Action

Functions as an occlusive emollient by forming a lipid barrier on skin surface to minimize water loss, while its twelve-carbon unsaturated structure integrates into existing skin lipids to enhance suppleness and provide a fatty base for enhanced delivery of other lipophilic actives.

Research

Clinical Evidence

Low confidence
Effective range ≤10%
Optimal

N/A

Key findings

  1. 01 10% concentration evaluated in dipropylene glycol showed acceptable safety profile at standard usage levels with noted skin irritation potential in concentrated forms

Transparency

Dusting Analysis

Not commonly dusted

Limited to specialty fragrance and emollient applications rather than broad cosmetic use due to irritation potential and stability concerns

The Formula

Formulation

Solubility
Oil
Optimal pH 4 – 8
0 7 14

Stability

Demonstrates excellent stability in fatty base systems but vulnerable to oxidative degradation when exposed to air and light, potentially developing rancid odors over time

Synergies

  • Dipropylene glycol
  • Other fatty alcohols
  • Lipid-replenishing components

Conflicts

  • Strong oxidizing agents
  • Strong acids

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

Classified as skin irritant (H315/R38) in pure form under GHS Category 2, regulated primarily under fragrance safety guidelines rather than cosmetic emollient standards

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

Limited efficacy data combined with moderate irritation risk makes this ingredient suitable only for specialized applications in non-sensitive skin formulations.

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