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Moumoujus

2-ACETONAPHTHONE.

Optional CAS 93-08-3 / FRAGRANCE, PERFUMING

A polycyclic aromatic ketone that serves as a fragrance component in skincare formulations, particularly valued for creating orange blossom and neroli accords. While effective at low concentrations, this lipophilic compound requires careful dosing due to its potential for phototoxic reactions when UV radiation interacts with its extended conjugated structure. Its primary role remains fragrance enhancement rather than active skincare benefits.

Summary

perfuming

Science

Mechanism of Action

Functions through its aromatic ketone structure to provide fragrance properties while interacting with skin lipids via its lipophilic nature (LogP ~2.68). The compound's extended conjugation allows absorption of UV radiation in the 290-400 nm range, which can lead to photo-excitation and subsequent phototoxic responses at elevated concentrations above 10%.

Research

Clinical Evidence

High confidence
Effective range 0.1–1%
Optimal

0.2%

Key findings

  1. 01 RIFM 2004 study demonstrated non-phototoxic and non-irritating properties at 0.1-1.0% concentrations
  2. 02 IFRA testing showed phototoxicity emergence at 10% concentration with increased erythema scores
  3. 03 Standard Draize testing confirmed skin irritation potential at 100% concentration

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
0.2%
Red flag below
10%

IFRA restricts this ingredient to 0.20% in fine fragrances due to documented phototoxicity above this threshold, making higher concentrations a safety concern rather than a dusting issue.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Demonstrates high stability under standard formulation conditions and maintains integrity in alkaline environments including soaps and detergents. The crystalline solid form can undergo sublimation at elevated temperatures.

Conflicts

  • Strong oxidizing agents
  • Strong bases
  • Strong reducing agents

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
0.2%
Sensitization risk Moderate

IFRA Category 4 restriction limits use to 0.20% due to phototoxicity concerns. FDA approves as synthetic flavoring agent (FEMA 2723) but skincare applications require sun exposure precautions.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Optional

A functional fragrance ingredient that requires precise dosing and sun protection awareness, suitable for non-sensitive skin types seeking enhanced scent profiles.

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