Science
Mechanism of Action
Functions through oxidative coupling chemistry where hydrogen peroxide triggers the formation of large, stable pigment molecules that permanently deposit within the hair shaft structure
Research
Clinical Evidence
High confidence0.25%
Key findings
- 01 SCCP safety assessment at 3.0% showed no skin irritation in repeated guinea pig applications
- 02 AICIS assessment confirmed 5.4 µg/cm² dermal absorption at 0.25% concentration with hydrogen peroxide
Transparency
Dusting Analysis
Not applicable to skincare formulations as this ingredient is exclusively used in hair coloring systems
The Formula
Formulation
Stability
Exhibits limited aqueous stability with 10% degradation within 48 hours at pH 3; demonstrates improved stability in cream base formulations lasting up to 8 weeks at 20°C
Synergies
- Hydrogen peroxide for oxidative activation
Conflicts
- Strong oxidizing agents outside controlled reactions
- Alkaline pH environments above 3.0
Safety
Safety Profile
SCCS approved for hair dye applications at maximum 0.25% concentration; classified as GHS Category 1A sensitizer with significant acute oral toxicity concerns
Your Skin
Skin Compatibility
Our Assessment
Verdict
Specialized hair dye ingredient with no skincare benefits and significant sensitization risks inappropriate for facial or body care formulations.
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References
Sources