2,6-DICARBOXYPYRIDINE

2,6-DICARBOXYPYRIDINE.

Optional CAS 499-83-2 / CHELATING

2,6-Dicarboxypyridine, also known as dipicolinic acid, is a synthetic chelating agent that binds metal ions to prevent oxidative damage in cosmetic formulations. This multifunctional ingredient primarily serves as a stabilizing agent, protecting other active ingredients from metal-catalyzed degradation while potentially offering protective benefits to skin DNA.

chelating stabilizing formulation enhancer

Science

Mechanism of Action

Functions as a metal chelator by forming stable complexes with iron, copper, and calcium ions, preventing these metals from catalyzing harmful oxidative reactions that can degrade skincare formulations and potentially damage skin cells

Research

Clinical Evidence

Low confidence

Effective range N/A

Optimal

N/A

Key findings

01 Related pyridine derivative showed hair density improvements at 1.5 months when combined with Resveratrol (PMID: 26084497)

Transparency

Dusting Analysis

Not commonly dusted

Primarily used as a stabilizing agent rather than a marketing active, making dusting unlikely

The Formula

Formulation

Solubility

Water

Optimal pH 2 – 7

0 7 14

Stability

Stable at room temperature with pKa of 2.16; enhanced solubility in hot water and alkaline conditions; decomposes under high heat

Synergies

Hydrogen peroxide formulations
Antioxidants requiring metal ion protection

Conflicts

Strong oxidizing agents
High temperature processing

Safety

Safety Profile

CIR Status

Not reviewed

Sensitization risk Low

Widely used in regulated hair care products as hydrogen peroxide stabilizer with low systemic exposure risk

Your Skin

Skin Compatibility

Yes Normal

Yes Dry

Yes Oily

Yes Sensitive

Irritancy Low

Comedogenicity Low

Our Assessment

Verdict

Optional

A reliable behind-the-scenes stabilizer that enhances formulation integrity rather than providing direct skin benefits.

Similar Ingredients

Finding similar ingredients…

References

Sources