Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

2,4-HEXADIENOL.

Avoid CAS 111-28-4 / PERFUMING

A multifunctional ingredient that serves as both a preservative and fragrance component, offering antifungal properties and photoprotective benefits. While research suggests potential in preventing UV-induced skin wrinkling through its ability to quench reactive oxygen species, significant safety concerns limit its application in modern skincare formulations.

Preservative Fragrance component Antifungal agent

Science

Functions as a triplet state quencher, intercepting excited molecular states to prevent formation of reactive oxygen species and free radicals from photosensitization reactions. Additionally provides antimicrobial activity by inhibiting molds and yeasts through disruption of fungal cellular processes.


Research

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Mouse study demonstrated protection against UVA-induced skin wrinkling but no effect on skin sagging (Bissett et al., 1990)
  2. 02 Identified as effective physical quencher of triplet excited states in photoprotection research (Wondrak et al., 2006)

Transparency

Not commonly dusted

Safety restrictions and regulatory prohibitions limit widespread cosmetic use, making dusting practices unlikely


The Formula

Solubility
Both
Optimal pH 6.5 – 9
0 7 14

Stability

Highly unstable in air with significant oxidation sensitivity requiring inert gas storage. Requires antioxidant stabilizers like alpha-tocopherol for formulation stability.

Synergies

  • Alpha-tocopherol for oxidative stability

Conflicts

  • Strong oxidizing agents
  • Strong acids
  • Heat sources
  • High-temperature processing

Safety

CIR Status
Not reviewed
Sensitization risk High

Classified as toxic skin contact agent (GHS Category 3) and skin/eye irritant (Category 2). Prohibited by IFRA for fragrance use and excluded from clean beauty standards including EWG approved lists.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Avoid

Despite potential photoprotective benefits, significant safety concerns and regulatory restrictions make this ingredient unsuitable for precision skincare applications.


Related

Finding similar ingredients…