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2,4-DIMETHYLBENZYLACETATE.

Optional CAS 62346-96-7 / PERFUMING

A synthetic fragrance ester that delivers floral and fruity scent notes while providing odor-masking capabilities in skincare formulations. This aromatic compound is particularly valued for its stability in acidic formulations and low sensitization potential at typical use concentrations.

perfuming masking

Science

Functions as a perfuming agent by binding to olfactory receptors to deliver pleasant scent characteristics. Upon contact with skin esterases, it undergoes hydrolysis to yield 2,4-dimethylbenzyl alcohol and acetic acid, allowing for controlled release of fragrance components.


Research

Medium confidence
Effective range ≤0.5%
Optimal

0.048%

Key findings

  1. 01 RIFM aggregate exposure modeling identified 0.048% as 95th percentile concentration in fine fragrances
  2. 02 Skin absorption studies on analog benzyl acetate demonstrate 17.3-78.7% dermal penetration based on occlusion conditions

Transparency

Not commonly dusted

Not applicable - this ingredient serves a functional perfuming purpose rather than active skincare benefits


The Formula

Solubility
Oil
Optimal pH 1 – 5
0 7 14

Stability

Demonstrates excellent stability in acidic environments (pH 1-5), making it particularly suitable for low-pH formulations. Susceptible to ester hydrolysis under highly alkaline conditions.

Conflicts

  • Strong oxidizing agents
  • Strongly alkaline environments

Safety

CIR Status
Not reviewed by CIR Panel
Max tested
0.5%
Sensitization risk Low

Regulated under IFRA standards with typical use levels below 0.1%. ECHA notes potential irritation only at 100% concentration, not at cosmetic use levels.


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Optional

A well-tolerated fragrance ingredient that serves its perfuming function effectively with minimal safety concerns at typical use concentrations.


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References