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Moumoujus

2,4-DIAMINOPHENOL.

Avoid CAS 95-86-3 / HAIR DYEING

An aromatic amine compound primarily functioning as an oxidative hair dye precursor rather than a conventional skincare ingredient. This chemical exhibits significant sensitization potential and is restricted to specific cosmetic applications due to safety concerns.

Summary

hair dyeing

Science

Mechanism of Action

Functions as a dye coupler that undergoes oxidation in the presence of hydrogen peroxide, forming quinone-imine intermediates that react with primary dye intermediates to create large polymeric pigment molecules

Research

Clinical Evidence

Medium confidence
Effective range ≤0.2%
Optimal

N/A

Key findings

  1. 01 FDA/CIR Safety Assessment establishing 0.2% maximum concentration for hair dye use
  2. 02 SCCS dermal absorption study showing 0.41-1.68% skin penetration at 2% concentration

Transparency

Dusting Analysis

Not commonly dusted

Not applicable to skincare formulations - this ingredient is restricted to hair dye applications only

The Formula

Formulation

Solubility
Water
Optimal pH 3 – 6
0 7 14

Stability

Requires acidic conditions for stability; rapidly degrades in alkaline environments with darkening. Most stable as dihydrochloride salt form. Light and heat sensitive.

Conflicts

  • Strong oxidizing agents
  • Strong acids
  • Transition metals
  • Alkaline environments

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
0.2%
Sensitization risk High

Known skin sensitizer and primary irritant. Prohibited for eye area use. Mutagenic potential at higher concentrations. Restricted to hair dye applications only.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

Not suitable for skincare applications due to high sensitization risk and restriction to hair dye use only.

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