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2,4,6-TRIMETHYL-4-PHENYL-1,3-DIOXANE.

Optional CAS 5182-36-5 / PERFUMING

A synthetic fragrance molecule commonly known by its trade name Floropal, delivering herbal, green, and citrus-like grapefruit notes to skincare formulations. This oil-soluble aroma chemical serves primarily as a scenting agent and odor-masking component in cosmetic products.

Perfuming Odor masking

Science

Functions as a fragrance component that masks unwanted odors while providing pleasant herbal and citrus scent notes. Patent literature suggests potential secondary antimicrobial effects against odor-causing skin bacteria like Staphylococcus epidermidis and Corynebacterium xerosis, though this is not its primary classification.


Research

Medium confidence
Effective range 0.1–1%
Optimal

0.5%

Key findings

  1. 01 Guinea pig Buehler testing demonstrated no sensitization reactions, confirming non-allergenic properties at this concentration level

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
2%

Standard cosmetic use remains well below safety thresholds, with typical concentrations ranging 0.1-1.0% versus maximum allowable 5.0%


The Formula

Solubility
Oil
Optimal pH 4 – 9
0 7 14

Stability

Demonstrates excellent stability in surfactant-based systems, soaps, and emulsions but degrades rapidly in oxidizing environments

Synergies

  • Fragrance oils
  • Surfactants
  • Emulsifying systems

Conflicts

  • Bleach
  • Strong oxidizing agents

Safety

CIR Status
Not reviewed
Max tested
5%
Sensitization risk Low

RIFM evaluation confirms non-genotoxic, non-phototoxic profile with Margin of Exposure >100 for repeated dose and reproductive endpoints


Your Skin

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Optional

A well-tolerated fragrance component suitable for most skin types, though unnecessary for sensitive skin formulations focused purely on efficacy.


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References