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2,3-BUTANEDIOL.

Valuable CAS 513-85-9; 5341-95-7; 24347-58-8 / FRAGRANCE, HUMECTANT, SKIN CONDITIONING, SOLVENT

A high-performance diol humectant that delivers superior hydration while serving as a multifunctional formulation enhancer. This biotechnology-derived ingredient excels at moisture retention and acts as a penetration booster for other actives.

Humectant Penetration enhancer Solvent Emulsion stabilizer Active ingredient booster

Science

Functions through dual hydroxyl groups that bind water molecules for enhanced skin hydration, while temporarily modifying stratum corneum lipid organization to improve active ingredient penetration and preventing crystallization of key components like ceramides


Research

Medium confidence
Effective range 1–10%
Optimal

5%

Key findings

  1. 01 10% concentration showed superior moisturizing and barrier improvement versus butylene glycol and glycerin
  2. 02 5% demonstrated enhanced penetration of co-formulated actives
  3. 03 1-10% range proven effective for humectant activity and emulsion stabilization

Transparency

Not commonly dusted

Functional ingredient used at meaningful concentrations (1-10%) rather than trace amounts for marketing purposes


The Formula

Solubility
Water
Optimal pH 5 – 6.5
0 7 14

Stability

Exceptionally stable with hygroscopic properties and low freezing point contributing to freeze-thaw resistance; risk of acetoin conversion above pH 7.0

Synergies

  • Vitamin C (enhanced stability and dispersion)
  • Ceramides (prevents crystallization)
  • Active ingredients (penetration enhancement)

Conflicts

  • Strong oxidizing agents
  • Strong acids (catalyze dehydration reaction)

Safety

CIR Status
Insufficient data (2018)
Max tested
25%
Sensitization risk Low

Despite insufficient CIR data, widely used in EU and Korean markets with typical usage up to 10%



Our Assessment

Valuable

Multifunctional ingredient that combines effective hydration with formulation benefits, though limited by insufficient regulatory safety data.


Related

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References