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10-HYDROXY-1,8-P-MENTHADIENE.

Insufficient Data CAS 15766-66-2 / PERFUMING

A monoterpene alcohol derivative, also known as Sobrerol, that functions primarily as a fragrance component with emerging evidence for antioxidant activity. This volatile terpene compound demonstrates hydroxyl radical scavenging properties at low concentrations while providing aromatic benefits to formulations. Its dual nature as both a perfuming agent and potential protective compound makes it an intriguing multifunctional ingredient.

Antioxidant Fragrance Skin conditioning

Science

Functions as a lipophilic monoterpene that penetrates skin barriers to neutralize hydroxyl radicals and reduce oxidative stress. The compound's p-menthadiene structure allows it to integrate into lipid-rich environments while its hydroxyl group enables direct radical scavenging activity.


Research

Low confidence
Effective range 0.0025–0.02%
Optimal

0.01%

Key findings

  1. 01 Significant hydroxyl radical scavenging activity demonstrated at 2.5-20 μg/ml concentrations
  2. 02 Anti-inflammatory and antioxidant bioactivity identified in monoterpene studies

Transparency

Not commonly dusted

Primarily used as a fragrance component at very low concentrations, making dusting unlikely and unnecessary for this application


The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Exhibits volatility typical of p-menthadiene compounds and requires protection from oxidizing conditions. Available in both water-soluble and oil-based forms depending on delivery system.

Conflicts

  • Strong oxidizing agents
  • Strong acids

Safety

CIR Status
Not reviewed
Sensitization risk Low

Listed in EU CosIng database as perfuming agent with established safety profile in pharmaceutical use. Contraindicated in children under 30 months due to terpene-related convulsion risk.



Our Assessment

Insufficient Data

Limited skincare research despite promising antioxidant activity warrants further investigation before definitive assessment.


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