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Moumoujus

1-HEXYL 4,5-DIAMINO PYRAZOLE SULFATE.

Avoid CAS 1361000-03-4 / HAIR DYEING

1-Hexyl 4,5-diamino pyrazole sulfate functions as an advanced precursor in oxidative hair dye systems. It contributes to the formation of long-lasting indo dyes, providing vibrant coloration to keratin fibers through a chemical reaction with specific couplers and oxidizing agents.

Summary

Hair Coloring Agent

Science

Mechanism of Action

This compound acts as an oxidative hair dye precursor. In the presence of an oxidizing agent, such as hydrogen peroxide, it undergoes a reaction with coupler compounds. This process forms indo dyes, which are responsible for imparting durable color to hair. The incorporated hexyl chain is thought to enhance its penetration into hair follicles due to improved lipid solubility, while the 4,5-diamino group actively participates in the necessary oxidative coupling reactions.

Research

Clinical Evidence

Insufficient-data confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

This ingredient is a hair dye precursor, not typically used in skincare formulations where 'dusting' might be a concern for active concentrations.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

1-Hexyl 4,5-diamino pyrazole sulfate demonstrates improved storage stability compared to its non-salt forms. Studies show high recovery rates (e.g., 99.39% after 7 days in 10% aqueous solution, 99.74% in water at pH 7.0, and 99.78% in a 1:1 water/ethanol mixture), indicating good stability in neutral aqueous and hydroalcoholic environments.

Conflicts

  • Oxidizing agents (reactants)
  • Coupler compounds (reactants)
  • Nitrosating agents (potential for byproduct formation)

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
1%
Sensitization risk Moderate

The SCCS deemed this ingredient safe for oxidative hair dye applications, provided the maximum on-head concentration does not exceed 1.0%. It is recognized as a moderate skin sensitizer. Its use is restricted to oxidative hair dye products, explicitly prohibiting application to eyelashes or eyebrows. Post-mixing, the final concentration applied to hair must remain at or below 1%. Product labels must advise wearing suitable gloves and explicitly state it should not be used on children under 3 years of age or on compromised skin (peeling or irritated).

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Avoid

This ingredient is a specific hair dye precursor with a known moderate skin sensitizer risk, making it unsuitable for precision skincare formulations.

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